Global Pulse Blog

Researchers at the J. Craig Venter Institute announced in Science that they created an experimental one-cell organism, Mycoplasma mycoides JCVI-syn1.0, that has the ability to reproduce.

An article written in the Wall Street Journal discusses the process used to create the cell:

To begin, they wrote out the creature’s entire genetic code as a digital computer file, documenting more than one million base pairs of DNA in a biochemical alphabet of adenine, cytosine, guanine and thymine. They edited that file, adding new code, and then sent that electronic data to a DNA sequencing company called Blue Heron Bio in Bothell, Wash., where it was transformed into hundreds of small pieces of chemical DNA, they reported.

To assemble the strips of DNA, the researchers said they took advantage of the natural capacities of yeast and other bacteria to meld genes and chromosomes in order to stitch those short sequences into ever-longer fragments until they had assembled the complete genome, as the entire set of an organism’s genetic instructions is called.

They transplanted that master set of genes into an emptied cell, where it converted the cell into a different species”

It may be possible for this new field, called synthetic biology, to one day provide alternatives to standard practices in many different industries. For example, the industrial life forms can be used to produce renewable fuels as well as vaccines.

This development also raises questions about concerning the ethics, law and public safety of artificial life. So I ask you all, what are some specific issues do you see needing to be addressed concerning synthetic life?

According to the World Health Organization, non-communicable diseases such as heart disease, cancer and diabetes, account for 60% of deaths worldwide, claiming more than 35 million lives per year. In all regions of the world except Africa, mortality rates among men and women age 15 to 59 are higher for non-communicable diseases than for communicable diseases. Further, The World Economic Forum recently highlighted the economic costs of non-communicable diseases, naming this health threat as one of the three most likely and severe risks to the global economy alongside fiscal crises and asset bubbles, a form of inflation. Yet despite this significant impact, non-communicable diseases tend to be overlooked and underfunded. For example, a Center for Global Development report estimates that less than 1% of public and private health funding is allocated to the prevention and control of non-communicable diseases in low- and middle-income countries. In response to this need for a greater focus on non-communicable diseases globally, a recent United Nations resolution has been introduced calling for a summit on non-communicable diseases “in order to develop strategic responses to these diseases and their repercussions.”

The CEOs of the American Heart Association, the American Cancer Society, and the American Diabetes Association comment on this issue in a recent (5/13) CNN opinion article.

Four months after the earthquake in Haiti, it is being argued that the poor are receiving better healthcare than before the quake due to the influx of medical volunteers and donated medicines, working under the supervision of the Ministry of Public health and Population.  In an effort to address the question of what will happen after the foreign medical aid leaves, the Post- Disaster Needs Assessment estimates that the earthquake resulted in US $169 million in damages to health infrastructure alone and in addition to that, their three-year plan to improve the country’s health profile beyond pre-January 12th levels will cost US $546 million. Currently, “Outside medical organizations are now the backbone of Haitian medical care,” says Dana Van Alphen, regional adviser for disaster management at the Pan American Health Organization who has been involved in discussions with a Haitian presidential health commission. In an effort to make these improvements in access to healthcare permanent, the PDNA identified primary health (along with  adequate  follow-up) and the establishment mobile clinics and health centers as a means to provide universal access, quality services and essential medications. This would allow care to be available nationwide instead of concentrated in Port-au- Prince.

The PDNA also recommends a massive investment in training for Haitian medical professionals because it is believed that now that the need for urgent care has subsided and the consequences of the earthquake are no ;longer front page news, the influx of foreign health professionals is fading. This transition would include pairing Haitian medical personnel with foreign staff for training and transferring functional control of hospitals and clinics to locals.

To begin the process proposed by the PDNA, a company called Containers to Clinics will transport a ready-made clinic, which will be transported in two pieces to the grounds of Graces Children’s Hospital in Port-au-Prince . The clinic is set to leave Boston around May 15 in a truck, which will haul it to Brooklyn, New York, where it will be loaded on a freight ship and be set up by June.

Please follow this link to read an executive summary of the PDNA.

This event is organized by the New York Medical Student Coalition Against Torture (NYMSCAT@gmail.com). Email to learn more, request materials, and get involved!

As I have written previously, medical professionals, students, and human rights groups in New York State are teaming up for action to pass the nation’s first law holding medical professionals accountable for assisting torture and abuse of prisoners.  AMSA is proud to join the list of organizations putting their support behind the proposed legislation:

• National Physicians Alliance
• Committee for Interns and Residents
• American College of Physicians-NY
• NY State Nurses Association
• NY Civil Liberties Union
• Center for Constitutional Rights
• Human Rights Watch
• Amnesty International
• Physicians for Human Rights
• I Have A Dream Foundation
• Metro NY Religious Campaign Against Torture
• (full list and statements at whenhealersharm.org/)

ANTI-TORTURE LOBBY DAY in Albany: Join AMSA and PHR with medical students from across the state in our first Anti-Torture Lobby Day in Albany on May 18th!  This is our chance to meet with our local lawmakers and tell them that ending torture is important to us as ethical medical professionals and Americans.  We will meet at 9AM for a white-coat press conference and advocacy training with experts from the Bellevue/NYU Program for Survivors of Torture, and follow up with advocacy meetings.  If you are a NY State resident and a medical or pre-medical student, don’t miss this chance for real-time local action for human rights!

Don’t forget to sign the petition: Stop Torture NY.org

Read AMSA’s statement of support after the cut:

Read the rest of this entry →

Farheen Qurashi, AMSA’s Jack Rutledge Legislative Director 2009-2010, and Mary Carol Jennings, AIDS Advocacy Network Chair 2009-2010, contributed to this post.  To join this event in NYC on May 13th, please contact Farheen at jrld@amsa.org.

On the campaign trail, President Obama pledged “to provide at least $50 billion by 2013 for the global fight against HIV/AIDS, including our fair share of the Global Fund, in order to at least double the number of HIV-positive people on treatment and continue to provide treatments to one-third of all those who desperately need them.”  HIV/AIDS patients and their advocates, including AMSA members, were important in getting then-candidates Obama, Clinton, and Biden to commit to these figures.

However, since taking office, the Obama Administration’s budgets have flatlined funding for AIDS programs.  Our commitments to fighting AIDS have not even kept pace with inflation: PEPFAR funding increased by only 2%  in 2010, while annual  inflation in most African countries is 7%.  Now, clinics around the world are reporting turning away patients with clinical AIDS who would previously have been treated, due to funding cuts (ITPC, 2010).

On May 13th, AMSA will be gathering for a white-coat protest at a Democratic Party fundraiser at St. Regis Hotel in NYC, to remind President Obama of his promises.  We will be joining activists from ACT UP, Africa Action, African Services Committee, NYC AIDS Housing Network, VOCAL-NY Users Union, Housing Works, Health GAP, Philadelphia Global AIDS Watchdogs, and other allies.  Join us, and let the President know that extending AIDS funding to meet the global need is important to you!  Please contact Mary Carol Jennings (marycaroljennings@gmail.com) for more details.

UPDATED: [05.11.2010] More information and disclaimer after cut. Read the rest of this entry →